PF14585 - CagY type 1 repeat

M3LCL2

Sequence:

>tr|M3LCL2|M3LCL2_HELPX DC-EC repeat protein (Fragment) OS=Helicobacter pylori GAM105Ai OX=1159022 GN=HMPREF1394_01765 PE=4 SV=1
SSDNHLDNPTETKTQETKTHFDEDKLEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVII
LFSRSIFHYFVPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFND
DPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDC
IKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERKECLKLINDPEI
REKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDE
ERNECLKNIPQDLQKELLADMSVKAYKDCVSRARNEKEKKECEKLLTPEARKKLEQQVLD
CLKNAKTDEERKKCLKNLPKDLQSDILAKESLKAYKDCASQAKTEAEKKECEKLLTPEAR
KLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAK
NEAERKECEKLLTPEARKLLENQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVRV
YLDCVSKAKNEAERKECEKLLTPEARKLLENQALDCLKNAKTDEERKECLKDLPKDLQKK
VLAKESVRVYLDCVSKA

MRF results:

Region 1: 468-605,69 aa length,2 units,T-REKS 1

SVKAYLDCVSQAKNEAERKECEKLLTPEARKLLENQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKE
SVRVYLDCVSKAKNEAERKECEKLLTPEARKLLENQALDCLKNAKTDEERKECLKDLPKDLQKKVLAKE

Region 2: 146-435,87 aa length,4 units,TRUST 0.99

ECISNGGNYEE---CLK-L--I---KDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVA-------L
DCLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIE--RLKQQ----A-------L
DCLKNAKTDEERNECLKNI--P---QDLQKELLADMSVKAYKDCVSRARNEKEKKECEKLLTPEARK--KLEQQ----V-------L
DCLKNAKTDEERKKCLKNL--P---KDLQSDILAKESLKAYKDCASQAKTEAEKKECEKLLTPEARK--LLEEE----AKESVKAYL

TAPAS results:

tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,structured domain,CATH,267,296,1.10.880.10/FF/719
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,structured domain,CATH,410,452,1.20.5.620/FF/543
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,transmembrane region,TMHMM,46,68
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,disordered region,IUPred,1,27
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,disordered region,BISMMpredictor,1,28
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,1,36,PF14585.7
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,176,201,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,215,239,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,256,287,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,288,318,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,325,356,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,357,387,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,394,424,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,433,463,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,471,501,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,503,533,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,541,570,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,functional domain,PFAM,572,602,PF07337.12
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,consensus ordered region,TAPASS,29,617
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,consensus disordered region,TAPASS,1,28
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,7,14,MOD_GSK3_1
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,11,17,MOD_PIKK_1
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,17,23,LIG_FHA_2
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,1,4,LIG_BIR_II_1
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,7,14,MOD_SUMO_rev_2
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,eukaryotic SLiMs,ELM,22,26,MOD_SUMO_rev_2
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,amyloidogenic region,Pasta,44,71
tr_M3LCL2GN=HMPREF1394_01765_PE=4_SV=1,amyloidogenic region,Tango,46,63

Alphafold results - spectrum b

Alphafold results - units from MRF

AlphaFold results M3LCL2