PF00414 - Neuraxin and MAP1B repeat

PF00414 Protein family information

P46821

Repeat units annotated: 1895-1911, 1929-1945, 1963-1979, 2031-2047 ,2048-2063 P46821 Interpro sequence information

Sequence:

>sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2
MATVVVEATEPEPSGSIANPAASTSPSLSHRFLDSKFYLLVVVGEIVTEEHLRRAIGNIE
LGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAV
STEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHP
ANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILPEMEGLSEFTEYLSESVEVP
SPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRH
LDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLN
VPENLKNPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIDPVILFQKMGVGKL
EMYVLNPVKSSKEMQYFMQQWTGTNKDKAEFILPNGQEVDLPISYLTSVSSLIVWHPANP
AEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRAD
SRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKP
SVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEV
AKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKE
VKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKG
KIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDF
EELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTE
GEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEE
HVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEA
DEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGRE
PASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPR
DVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDY
NASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLS
PSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEV
VSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPM
DEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPD
QVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDV
SPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATS
SFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSIS
PPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHIT
ENGPTEVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQ
IASPLQEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRESSPLYSPTF
SDSTSAVKEKTATCHSSSSPPIDAASAEPYGFRASVLFDTMQHHLALNRDLSTPGLEKDS
GGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGYYYEKIERTTKSPSDSG
YSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPEVSGYSYEKTERS
RRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSYETSTKTTRTPDTSTY
CYETAEKITRTPQASTYSYETSDLCYTAEKKSPSEARQDVDLCLVSSCEYKHPKTELSPS
FINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDS
DVPPETEECPSITADANIDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMV
DPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKES
SDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPG
TTKTTKSSAVPPGLPVYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRA
VLDALLEGKAQWGSNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDES
FPACKIEL

MRF results:

Region 1: 2025-2058, 17 aa length, 2 units
YETSTKTTRTPDTSTYC
YETAEKITRTPQASTYS

Region 2: 1921-1971, 17 aa length, 3 units
YSYETIGKTTKTPEDGD
YSYEIIEKTTRTPEEGG
YSYDISEKTTSPPEVSG

Region 3: 690-737, 5 aa length, 12 units
KEEK-
KEPK-
KEVK-
KETPP
KEVK-
KEVK-
KEEK-
KEVK-
KEE--
KEPK-
KEIK-
KLPK-

TAPAS results:

sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,structured domain,CATH,263,447,3.60.15.10/FF/29172
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,structured domain,CATH,461,491,3.60.15.10/FF/29223
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,1,21
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,331,344
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,521,786
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,793,1225
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,1238,1826
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,1846,2072
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,2094,2349
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,2396,2402
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,IUPred,2429,2434
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,189,208
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,330,345
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,530,547
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,550,570
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,588,617
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,633,660
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,661,748
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,755,771
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,878,914
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,932,963
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1008,1028
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1083,1114
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1143,1159
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1184,1201
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1205,1222
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1246,1278
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1321,1336
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1337,1352
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1378,1393
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1415,1444
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1467,1482
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1558,1575
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1595,1646
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1688,1719
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1771,1786
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1807,1823
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1847,1869
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1872,1888
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1907,1922
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1924,1939
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,1985,2007
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,2024,2041
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,2085,2101
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,2111,2173
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,2177,2194
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,disordered region,BISMMpredictor,2235,2268
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,1878,1894,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,1895,1911,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,1912,1926,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,1929,1945,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,1963,1979,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,2031,2047,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,functional domain,PFAM,2048,2063,PF00414.18
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus ordered region,TAPASS,22,188
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus ordered region,TAPASS,209,520
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus ordered region,TAPASS,2350,2395
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus ordered region,TAPASS,2435,2467
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus disordered region,TAPASS,1,21
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus disordered region,TAPASS,189,208
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus disordered region,TAPASS,521,2349
sp_P46821_OX=9606_GN=MAP1B_PE=1_SV=2,consensus disordered region,TAPASS,2396,2434,
_images/P46821tapass.jpg

Alphafold results - spectrum b

_images/P46821alphafold.png

Alphafold results P46821